Gasdermin C and its association with prognosis of cancer
10.3781/j.issn.1000-7431.2025.2309-0497
- VernacularTitle:Gasdermin C与肿瘤预后关系的研究进展
- Author:
Yanan WANG
1
;
Jiafu LIU
1
;
Dongmei ZHANG
1
;
Lin WANG
1
Author Information
1. 哈尔滨医科大学大庆校区基础医学院,黑龙江 大庆 163319
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Pyroptosis;
Gasdermin C
- From:
Tumor
2025;45(1):93-100
- CountryChina
- Language:Chinese
-
Abstract:
Gasdermin family proteins play critical roles in cell pyroptosis.Previous studies mainly focused on the function of Gasdermin D and Gasdermin E,less attention has been paid to Gasdermin C.Recently,accumulating studies revealed some distinctive characters of Gasdermin C different from other Gasdermin proteins and the impact of Gasdermin C on the prognosis of different types of tumor.This review summarized the recent study progresses in terms of molecular structure of Gasdermin C,the Gasdermin C mediated pyroptotic pathway as well as the prognostic significance of Gasdermin C in tumors,by which to provide informative references for corresponding researchers.
