Whole brain CT perfusion combined with artificial intelligence iterative reconstruction for evaluating acute ischemic stroke
10.13929/j.issn.1003-3289.2025.04.002
- VernacularTitle:全脑CT灌注联合深度学习全模型迭代算法用于评估急性缺血性脑卒中
- Author:
Minke WANG
1
;
Tiantian WANG
;
Jinbiao HUANG
;
Youyou LIN
;
Jicheng XIE
Author Information
1. 浙江省台州医院放射科,浙江 台州 317000
- Publication Type:Journal Article
- Keywords:
stroke;
tomography,X-ray computed;
perfusion imaging;
angiography
- From:
Chinese Journal of Medical Imaging Technology
2025;41(4):515-519
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of whole brain CT perfusion(CTP)-derived arterial phase images combined with artificial intelligence iterative reconstruction(AIIR)for evaluating acute ischemic stroke(AIS).Methods Fifty AIS patients were prospectively enrolled,and whole brain CTP followed by routine CT angiography(CTA)were performed.CTP images were reconstructed using AIIR(CTP-AIIR group)and hybrid iterative reconstruction(HIR,CTP-HIR group),respectively,and CTA images were derived from CTP at the arterial phase.Meanwhile,routine CTA images were obtained using HIR(CTA-HIR group).Then image quality was subjectively evaluated with a 5-point scale.The noise of basilar artery trunk,cavernous segment of internal carotid artery,M1 segment of middle cerebral artery and the brain parenchyma were calculated,and signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of the above 3 arteries were measured.Taken digital subtraction angiography as the reference standard,the accuracy of CTP and CTA for localizing the responsible vessel of AIS was assessed.Results In CTP-AIIR group,the subjective scoring of 4 subjective metrics,including image noise,sharpness of vessel margin,small vessel visibility and overall diagnosability were significantly higher than,the noise of 3 arteries and brain parenchyma were lower than,and SNR and CNR of 3 arteries were higher than those in CTP-HIR group and CTA-HIR group(all P＜0.017).The diagnostic accuracy of responsible vessel based on CTP-AIIR group and CTA-HIR group were both 96.00％ (48/50),not significantly different with that in CTP-HIR group(44/50,88.00％ )(P=0.142).Conclusion Whole brain CTP-derived arterial phase CTA combined with AIIR could achieve comparable image quality and diagnostic performance of routine CTA for evaluating AIS.
