Imaging findings of 10 cases of misdiagnosis IgG4-associated pancreatitis
10.13929/j.issn.1003-3289.2025.04.024
- VernacularTitle:10例误诊IgG4相关性胰腺炎的影像学表现
- Author:
Huawei XIA
1
;
Wenya ZHU
;
Hongjie HU
;
Ling WEN
Author Information
1. 浙江大学医学院附属邵逸夫医院放射科,浙江 杭州 310016
- Publication Type:Journal Article
- Keywords:
immunoglobulin G4-related disease;
pancreatitis;
diagnostic errors;
tomography,X-ray computed;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(4):622-626
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore imaging findings of 10 cases of misdiagnosed IgG4-associated pancreatitis.Methods Ten cases of IgG4-associated pancreatitis misdiagnosed by preoperative CT and/or MRI were retrospectively collected,and intrapancreatic and extra pancreatic manifestations were observed.Results Among 10 cases,diffuse lesions resulted"sausage like"appearance of pancreas were observed in 2 cases,focal lesions were found in 7 cases,including 3 cases in neck,3 cases in head and 1 case in tail of pancreas,while multifocal lesions involved the head,neck and tail of pancreas in 1 case.The lesions mostly presented as slightly low densities and occasional calcifications on non-enhanced CT,slightly low signals on MR T1WI,equal or high signals on T2WI as well as slightly high signals on diffusion weighted imaging,and progressively enhanced after administration of contrast agents.Peripheral halo sign was found in 3 cases,and mild dilatation of main pancreatic duct was observed in 7 cases.Extrapancreatic manifestations mainly included dilatation of bile ducts both inside and outside the liver and involvement of other organs.Conclusion Imaging findings of misdiagnosis IgG4-associated pancreatitis present as focal or diffuse lesions of pancreas with peripheral halo sign and extrapancreatic involvements,which progressively enhanced after administration of contrast agents.
