Analysis of the Mechanism of ZHANG Zhongjing Rejuvenation Method with Wind Medicine in the Treatment of Late-Pulse Heart Disease
10.16466/j.issn1005-5509.2025.03.005
- VernacularTitle:张仲景风药复脉法治疗迟脉型心病之机制探析
- Author:
Jiankang WANG
1
;
Lujia CHEN
;
Dan CHEN
Author Information
1. 浙江中医药大学附属宁波市中医院 宁波 315010
- Publication Type:Journal Article
- Keywords:
late-pulse heart disease;
refractory bradycardia;
wind herbal restoring pulse;
ZHANG Zhongjing;
Treatise on Febrile Diseases;
Synopsis of the Golden Chamber;
basic pathogenesis;
mechanism of action
- From:
Journal of Zhejiang Chinese Medical University
2025;49(3):292-299
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To explore and discuss the mechanism of ZHANG Zhongjing's methods of wind medicine in treating delayed-pulse heart disease by applying the theory of wind medicine in Neijing and the understanding of wind medicine by medical practitioners throughout the history.[Methods]Summarize ZHANG Zhongjing's compilation of Treatise on Febrile Diseases and Synopsis of the Golden Chamber,explore the etiology and pathogenesis of delayed-pulse heart disease,as well as the mechanism of wind medicine for restoring meridians,and use modern pharmacological research to demonstrate the effective ingredient targets of wind medicine.[Results]It was found that the causes of wind-induced delayed-pulse included external wind evil,internal liver wind,wind damaging heart Qi and evil obstructing heart meridians which were its basic pathogenesis.The treatment methods of tonifying the heart and supporting the essence,dispelling wind and unblocking the meridians were the main methods.Based on this,a wind medicine complex pulse treatment method was established,and Zhongjing's differentiation and medication were classified into 9 types and 9 methods,forming a series of treatment frameworks,including:regulating and tonifying the Ying Wei,dispelling wind and dispelling evil,clearing upper and warming lower,dispelling wind and dispersing toxins,nourishing Qi and blood,dispelling wind and removing Bi,unblocking Yang and dispersing cold,calming the Ying Wei,resolving phlegm and promoting stagnation,promoting Bi and unblocking the meridians,promoting and clearing spleen,invigorating Qi for relieving desertion,warming kidney and nourishing essence,stimulating Wei Qi,promoting lung and strengthening heart,warming water and drinking method,dispelling wind and unblocking meridians,promoting blood circulation and removing stasis.Furthermore,the mechanism of action of wind medicine in restoring meridians was analyzed,including expelling external wind,relieving liver and dispelling wind,harmonizing Yin and Wei,promoting spleen and clearing blood,resolving phlegm and dampness,promoting blood circulation and unblocking collaterals,nourishing blood,and calming the heart and mind.This was confirmed to be consistent with the effective ingredient targets of modern pharmacological research on wind medicine.[Conclusion]The Zhongjing wind herbal pulse restoration method has significant theoretical guidance and clinical application value in the diagnosis and treatment of refractory bradycardia.
