Analysis of the Distribution of Characteristics and Combination Rules of Syndrome Elements in Recurrent Oral Ulcers Based on Literature Review
10.16466/j.issn1005-5509.2025.03.011
- VernacularTitle:基于文献回顾探析复发性口腔溃疡的证素分布特点及组合规律
- Author:
Tianxiao FU
1
;
Wenwen LU
1
;
Fenglin HU
1
Author Information
1. 浙江大学医学院附属第一医院 杭州 310003
- Publication Type:Journal Article
- Keywords:
recurrent oral ulcer;
heart-spleen heat accumulation;
syndrome elements;
disease location;
disease nature;
syndrome;
traditional Chinese medicine;
literature review
- From:
Journal of Zhejiang Chinese Medical University
2025;49(3):326-332
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To summarize the distribution characteristics and mutual combination rules of syndrome elements through the extraction of syndrome elements from recent literature on recurrent oral ulcers,analyze the etiology and pathogenesis and provide theoretical basis for clinical diagnosis and treatment in traditional Chinese medicine.[Methods]The clinical literature related to recurrent oral ulcers in the past four years in the China National Knowledge Infrastructure and WanFang databases was searched,key information such as syndromes and syndrome elements was extracted,an information database was established,and frequency analysis was conducted.[Results]One hundred and sixty-one literatures were included,and 26 standard Chinese medicine syndromes for recurrent oral ulcers were extracted.Heart-spleen heat accumulation syndrome was the most common,followed by Yin deficiency and fire hyperactivity syndrome,dampness-heat due to spleen deficiency syndrome,phlegm and blood stasis were the least common.A total of 8 disease location syndrome elements were extracted from the spleen,heart,stomach,liver,kidney,gallbladder,lung and large intestine.The most common disease location syndrome was the spleen,followed by the heart,and the large intestine was the least frequent.Fourteen disease syndrome elements including heat,blood deficiency,and poison were extracted.The most common was heat,followed by Yin deficiency,and dryness was the least frequent.There were 10 combinations of syndrome elements,among which spleen+heat,heart+spleen+heat,heart+fire were the most frequent,and liver+blood deficiency was the least frequent.[Conclusion]The main type of recurrent oral ulcers is characterized by heart-spleen heat accumulation,which is most closely related to the spleen,the pathological factor is heat.Clinical treatment of recurrent oral ulcers often starts with the three organs of the spleen,heart and stomach,with the three most important methods of reducing fire,clearing heat and eliminating dampness.
