Analysis of the distribution of high-risk human papillomavirus subtypes and high-risk factors among women in Jiaxing
10.3969/j.issn.1673-9701.2025.13.012
- VernacularTitle:嘉兴市女性高危型人乳头瘤病毒亚型分布及高危因素分析
- Author:
Xiaoji CAI
1
;
Xiaojie WU
;
Guoya ZHU
Author Information
1. 嘉兴市妇幼保健院妇科,浙江嘉兴 314050
- Publication Type:Journal Article
- Keywords:
High-risk human papillomavirus;
Screening;
Age;
Education background;
Risk factors
- From:
China Modern Doctor
2025;63(13):52-54,88
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of high-risk human papillomavirus(HR-HPV)subtypes and risk factors in Jiaxing,so as to provide reference for cervical cancer screening in high-risk population.Methods A total of 22 573 women from Zhejiang cervical cancer screening project management system from April to October 2023 were selected for HR-HPV screening,and they were divided into HR-HPV positive group(2045 cases)and negative group(20 528 cases).The medical history data of the patients were analyzed,and the risk factors of HR-HPV infection were analyzed by univariate and multivariate regression analysis.Results The overall HR-HPV infection rate was 9.06％.HPV52 was the most common type in single infection(29.6％),and HPV2 was the most common type in multiple infections(13.0％).There were significant differences between HR-HPV positive group and negative group in age,education level,gravidity,number of abortions and different neighborhoods(P＜0.05).Multivariate Logistic regression analysis showed that age＞45 years old,primary school education or below,gravidity were independent risk factors for HR-HPV infection.Conclusion HPV52 is the predominant type of HR-HPV in Jiaxing.Age＞45 years,primary school education or below,and gravidity are related risk factors for HR-HPV infection.These populations should still focus on screening,which has a pivotal role in the prevention and treatment of cervical lesions.
