Data Mining Study on Xin'an Doctors for the Treatment of Liver Cirrhosis Based on Symptoms-Syndromes-Medicines
10.19879/j.cnki.1005-5304.202411682
- VernacularTitle:基于症状-证候-药物的新安医家治疗肝硬化数据挖掘研究
- Author:
Hui WANG
1
;
Huiyuan ZHENG
;
Jingxi FENG
;
Wen LI
;
Jili HU
;
Peng WU
Author Information
1. 安徽中医药大学第一临床医学院,安徽 合肥 230012
- Publication Type:Journal Article
- Keywords:
liver cirrhosis;
Xin'an medicine;
syndromes;
symptoms;
medication;
data mining
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(6):45-51
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of Xin'an doctors in the syndrome differentiation and treatment of liver cirrhosis from the dimensions of symptoms,syndromes and medication using data mining methods.Methods Medical cases and prescriptions for liver cirrhosis were collected from Xin'an medical literature.Data mining was performed using frequency analysis,complex network analysis,Louvain clustering analysis and factor analysis to investigate syndromes,symptoms,and medicines.Results A total of 363 prescriptions were analyzed,involving 15 syndromes and 325 kinds of Chinese materia medica,with 33 identified as core medications.Tonifying herbs were the most frequently used;the primary syndromes were liver qi stagnation and water retention;core symptoms of liver qi stagnation included emotional distress,reduced appetite and hypochondriac pain,with core medications such as Bupleuri Radix and Poria;core symptoms of water retention included lower limb edema and abdominal distension,with core medications such as Pinelliae Rhizoma,Citri Reticulatae Pericarpium,Magnoliae Officinalis Cortex and Poria.Factor analysis of core medications identified 12 common factors.Conclusion The pathogenesis of liver cirrhosis involves deficiency in nature and excess in superficiality,primarily affecting the liver and closely related to the spleen and kidneys.Xin'an doctors emphasize treating the symptoms with qi-regulating,blood-activating,dampness-drying and heat-clearing strategies,while simultaneously addressing the root with qi-tonifying,spleen-strengthening,liver-nourishing and kidney-replenishing therapies.
