Application of cardiac magnetic resonance myocardial strain technology in elderly men with hypertrophic cardiomyopathy
10.3969/j.issn.1009-0126.2025.05.002
- VernacularTitle:心脏磁共振心肌应变技术在老年男性肥厚型心肌病中的应用研究
- Author:
Xue ZHENG
1
;
Bingqi KANG
;
Jinjin CUI
;
Guanzhong LIU
;
Xinjiang WANG
;
Xue YANG
;
Shuxia WANG
;
Ping ZHU
;
Hongxiang YAO
Author Information
1. 100853 解放军总医院第二医学中心放射诊断科 国家老年疾病临床医学研究中心
- Publication Type:Journal Article
- Keywords:
multiparametric magnetic resonance imaging;
cardiomyopathy,hypertrophic;
logistic models;
myocardial strain
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(5):548-553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of CMR myocardial strain technique in eld-erly males with HCM.Methods A retrospective analysis was conducted on 50 elderly male pa-tients who underwent CMR examination at the Second Medical Center of Chinese PLA General Hospital from April 2020 to December 2024.According to being diagnosed with HCM or not,they were divided into a HCM group(24 cases)and a control group(26 cases).Post-processing soft-ware CVI42 was used to obtain two sets of basic functional and strain parameters of the left ven-tricle(LV)and left atrium(LA).The parameters of LV included LV mass,LV mass index(LV massi),global longitudinal strain(GLS),and so on,while the parameters of LA included minimum LA volume(LAV),minimum LA volume index(LA VI),LA passive strain(εe),LA peak early negative strain rate(SRe)and LA peak late negative strain rate(SRa),etc.The two sets of LV and LA parameters of basic functional and strain were compared between the two groups.Results The HCM group had significant higher LV mass and LV massi and minimum LAV and LAVI,but lower GLS,εe,SRe and SRa in 2D and 3D speckle-tracking echocardiography than the control group(P＜0.05,P＜0.01).The AUC value of 2D GLS,SRa,and logistic regres-sion model in predicting HCM was 0.887(95％CI:0.766-0.959),0.740(95％CI:0.597-0.854),and 0.929(95％CI:0.820-0.983),respectively,with a sensitivity of 76.92％,57.69％,and 84.62％,and a specificity of 70.83％,83.33％,and 91.67％,respectively.The logistic regression model demonstrated higher AUC value,sensitivity,and specificity than 2D GLS and SRa.Conclusion CMR myocardial strain technology is of significant diagnostic value for elderly male patients with HCM.
