Analysis on influencing factors of postoperative absorption effect of microwave ablation for papillary thyroid microcarcinoma
10.3969/j.issn.1672-8270.2025.05.002
- VernacularTitle:微波消融治疗甲状腺微小乳头状癌术后吸收效果的影响因素分析
- Author:
Xinran CAO
1
;
Ruifang GUO
1
;
Peipei YANG
1
;
Linxue QIAN
1
Author Information
1. 首都医科大学附属北京友谊医院超声科 北京 100050
- Publication Type:Journal Article
- Keywords:
Papillary thyroid microcarcinoma(PTMC);
Microwave ablation(MWA);
Influencing factor;
Ultrasonography features
- From:
China Medical Equipment
2025;22(5):6-9,15
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influencing factors of absorption effect postoperative ablation area after microwave ablation(MWA)for papillary thyroid microcarcinoma(PTMC).Methods:The clinical and ultrasound data of 101 patients with single PTMC who underwent microwave ablation in Beijing Friendship Hospital between April 2019 and July 2023 were collected.According to the endpoint event of whether the ablation area disappeared one year after MWA,they were divided into disappearance group(52 cases)and non-disappearance group(49 cases).Univariate and multivariate logistic regression were used to analyze the factors of affecting the absorption effect of ablation area,and a regression model was constructed.Receiver operating characteristic(ROC)curve was drawn to test the predictive efficacy of the model.Results:There were significant differences in the age,coarse calcification in the nodule,ablation time,Hashimoto's thyroiditis between two groups(x2=4.708,12.180,19.497,8.457,P<0.05),respectively.There were also significant differences in maximum diameter of nodule,nodule volume,ablation energy between two groups(Z=-3.929,-3.969,-3.677,P<0.05).Multivariate logistic regression analysis showed that age≥50 years old,coarse calcification in the nodule,ablation time≥50s,and Hashimoto's thyroiditis were independent influencing factors for the non-disappearance of ablation area one year after MWA for PTMC(OR=4.464,3.733,10.063,4.173,P<0.05).The ROC curve analysis showed that the area under curve(AUC)of the regression model in predicting non-disappearance of ablation area after MWA for PTMC was 0.853(95%CI:0.777-0.929),and the diagnostic sensitivity and specificity of that were respectively 75.5%and 82.7%.Conclusion:The logistic regression model,that is constructed on the basis of clinical information,preoperative ultrasound features,and thermal ablation parameters,has high clinical application value in predicting the postoperative absorption of the ablation area in patients who undergo MWA for PTMC.
