Research Progress in Chinese Materia Medica Regulating GABA for the Treatment of Anxiety Disorders
10.19879/j.cnki.1005-5304.202410465
- VernacularTitle:中药调控γ-氨基丁酸治疗焦虑症研究进展
- Author:
Haipeng GUO
1
;
Tingting WANG
1
;
Manshu ZOU
1
;
Hongqing ZHAO
1
;
Yuhong WANG
1
Author Information
1. 湖南中医药大学科技创新中心,中药粉体与创新药物国家重点实验室培育基地,湖南 长沙 410208
- Publication Type:Journal Article
- Keywords:
TCM monomers;
compound prescriptions;
anxiety disorder;
gamma-aminobutyric acid;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(6):193-196,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Anxiety disorder is a common emotional disorder,with its pathological mechanisms involving the imbalance of multiple neurotransmitter systems,especially the dysfunction of the gamma-aminobutyric acid(GABA)system.This article explored the TCM understanding of anxiety disorder,and summarized and organized the research on the regulation of GABA system in the treatment of anxiety disorders through TCM monomers and formulas from the aspects of terpenes,flavonoids,phenolic acids,lignans,cinnamic acids,saponins,etc.At present,the research mainly involved chrysin,baicalin,ginsenoside,Baihe Dihuang Decoction,Bentun Decoction,Suanzaoren Decoction,Chaihu Jia Longgu Muli Decoction,etc.The mechanism involved regulating the inflammatory response of the body,alleviating oxidative stress damage,restoring the hyperactive HPA axis and other action pathways,which could provide a reference for the related research of TCM anti anxiety treatment and the development of new drugs.
