The diagnostic value of endoscopic ultrasound-guided fine needle aspiration in biliary lesions and factors influencing its accuracy
10.12354/j.issn.1000-8179.2025.20250332
- VernacularTitle:超声内镜引导下细针穿刺对胆管病变的诊断价值及其准确性影响因素
- Author:
Tan XIANHAO
1
;
Zhou XI
;
Zhao MING
;
Jiang LIN
;
Sun XIAOBIN
;
Shan JING
Author Information
1. 西南医科大学附属医院消化内科(四川省 泸州市 646000)
- Publication Type:Journal Article
- Keywords:
endoscopic ultrasound-guided fine needle aspiration(EUS-FNA);
biliary cancer;
endoscopic ultrasound;
diagnostic effi-ciency;
needle size
- From:
Chinese Journal of Clinical Oncology
2025;52(11):565-570
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the diagnostic performance and safety of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)for biliary lesions and to investigate the factors influencing its accuracy.Methods:A retrospective analysis was performed on the clinical data of patients who underwent EUS-FNA at Chengdu Third People's Hospital between January 2021 and December 2023 for suspected malig-nant biliary strictures or masses,including 22 males and 19 females,with a mean age of 65.9(35.0-89.0)years.Diagnostic performance(sensitivity,specificity,positive predictive value,negative predictive value,and accuracy)and factors influencing these outcomes were evalu-ated.Results:The overall sensitivity of EUS-FNA for diagnosing biliary lesions was 85%,with a specificity of 100%,positive predictive value of 100%,negative predictive value of 33%,and accuracy of 86%.The use of a 25G needle and the presence of solid masses were significant factors influencing the diagnostic accuracy of EUS-FNA.In contrast,the puncture site did not impact diagnostic performance.No EUS-FNA-re-lated adverse events were observed during the follow-up period.Conclusions:EUS-FNA is highly accurate and safe for the diagnosis of bili-ary lesions.The diagnostic accuracy of EUS-FNA significantly improves when using a 25G needle and in the presence of solid biliary masses.
