Enhanced MRI"strawberry sign"for differentiating solitary predominantly cystic brain metastasis and glioma
10.13929/j.issn.1003-3289.2025.06.009
- VernacularTitle:基于增强MRI"草莓征"鉴别囊性为主单发脑转移癌与胶质瘤
- Author:
Bofeng ZHAO
1
;
Wei FENG
1
;
Xiaohan GUO
1
;
Ping CHEN
1
;
Xiaolong FAN
1
;
Baoying CHEN
1
Author Information
1. 西安国际医学中心医院影像诊疗中心,陕西西安 710700
- Publication Type:Journal Article
- Keywords:
brain neoplasms;
neoplasm metastasis;
glioma;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(6):888-891
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of enhanced MRI"strawberry sign"for differentiating solitary predominantly cystic brain metastasis and glioma.Methods Thirty-four patients with solitary predominantly cystic(cystic proportion greater than 50％)brain metastasis(metastasis group)and 43 with solitary predominantly cystic glioma(glioma group)were retrospectively enrolled,and the value of"strawberry sign"showed on contrast enhanced T1WI(CE-T1WI)for differentiation was analyzed.Results The detection rate of"strawberry sign"in metastasis group was 44.12％(15/34),and the primary cancer was lung adenocarcinoma in 6 cases(6/15,40.00％),small cell lung cancer in 3 cases(3/15,20.00％),as well as lung squamous cell carcinoma,breast cancer,colon adenocarcinoma,endometrioid carcinoma,fallopian tube adenocarcinoma and rectal melanoma each in 1 case(1/15,6.67％).Meanwhile,the detection rate of"strawberry sign"in glioma group was 18.60％(8/43),and all were observed in WHO grade 4 gliomas.The detection rate of"strawberry sign"in metastasis group was higher than that in glioma group,which was not related to patients' gender(P=0.442).The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of"strawberry sign"for differentiating solitary predominantly cystic brain metastasis and glioma was 44.12％,81.40％,64.94％,65.22％and 64.81％,respectively.Conclusion"Strawberry sign"showed on CE-T1WI was helpful for differentiating solitary predominantly cystic brain metastasis and glioma.
