Quantitative CT analysis of human body components for predicting microvascular invasion status of hepatocellular carcinoma
10.13929/j.issn.1003-3289.2025.06.020
- VernacularTitle:基于定量CT分析人体组分预测肝细胞癌微血管浸润状态
- Author:
Zhecheng CHENG
1
;
Jian ZHAI
;
Qi HONG
;
Min HU
;
Wenwei YE
Author Information
1. 黄山市人民医院CT/MRI室,安徽黄山 245000
- Publication Type:Journal Article
- Keywords:
carcinoma,hepatocellular;
microvascular invasion;
tomography,X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2025;41(6):943-946
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of quantitative CT(QCT)analysis of human body components for predicting microvascular invasion(MVI)status of hepatocellular carcinoma(HCC).Methods Totally 60 HCC patients were retrospectively enrolled and divided into positive group(n=15)and negative group(n=45)based on postoperative pathology findings of MVI or not.Human body composition parameters,including bone mineral density(BMD),subcutaneous fat area(SFA),visceral fat area(VFA),total fat area(TFA)and subcutaneous/visceral fat area ratio(SVR),as well as muscle fat area(MFA),muscle area(MA)and muscle fat infiltration(MFI)of posterior vertebral muscle group based on QCT were compared between groups,and the efficacy of the above parameters for predicting MVI status of HCC was observed.Results SFA,TFA,MFA and MFI were all higher,while MA was lower in positive group than those in negative group(all P＜0.05).The area under the curve(AUC)of SFA,VFA,TFA,MA,MFA and MFI for predicting MVI status of HCC ranged from 0.673 to 0.790(all P＜0.05).TFA and M FI were both independent risk factors of HCC MVI(both P＜0.05),with AUC of 0.790 and 0.759,respectively.Conclusion QCT analysis of human body components was helpful to predicting MVI status of HCC.
