Value of HDL-C in predicting the outcome of amputation in patients with diabetic foot
10.3969/j.issn.1673-9701.2025.05.010
- VernacularTitle:HDL-C水平对糖尿病足患者截肢结局的预测价值
- Author:
Xiangyu LYU
1
;
Lijue REN
;
Yanqing ZHAO
Author Information
1. 内蒙古科技大学包头医学院研究生学院,内蒙古包头 014040;内蒙古科技大学包头医学院第一附属医院内分泌科,内蒙古包头 014010
- Publication Type:Journal Article
- Keywords:
High density lipoprotein cholesterol;
Diabetic foot;
Amputation;
Predictive value
- From:
China Modern Doctor
2025;63(5):35-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of high density lipoprotein cholesterol(HDL-C)in predicting the risk of amputation in patients with diabetic foot(DF).Methods A total of 110 DF patients hospitalized in the First Affiliated Hospital of Baotou Medical College from August 2020 to June 2024 were selected as the study subjects,including 23 patients in amputation group and 87 patients in non-amputation group according to whether amputation.The related data of two groups were compared.Binary Logistic regression analysis was used to explore the influencing factors of amputation in DF patients,and receiver operating characteristic curve(ROC)was used to analyze and compare the predictive value of HDL-C combined with other possible risk factors for amputation outcome.Results A total of 110 patients were included in this study,and binary Logistic regression analysis showed that HDL-C,length of stay,uric acid,and lower extremity arterial disease were the influential factors for amputation in diabetic foot patients(P<0.05).HDL-C combined with lower extremity arterial disease can improve the ability to predict the outcome of amputation.Conclusion HDL-C level is an influential factor in the amputation of DF patients,and has a certain predictive value for the amputation of DF patients.