Meta-analysis of risk factors of hospitalization infections in patients with multiple myeloma after chemotherapy
10.3969/j.issn.1673-9701.2025.06.006
- VernacularTitle:多发性骨髓瘤化疗后患者住院感染危险因素的Meta分析
- Author:
Yuelin WANG
1
;
Yunlan JIANG
;
Le LI
;
Hong CHEN
;
Jing WANG
;
Mengjie ZHANG
;
Xiaoyu BAI
;
Senlin WU
Author Information
1. 成都中医药大学护理学院,四川成都 610075
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Chemotherapy;
Hospitalization infections;
Risk factors;
Meta-analysis
- From:
China Modern Doctor
2025;63(6):30-34,94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate influence factors hospitalization infections in multiple myeloma(MM)patients after chemotherapy.Methods Computer searches were conducted on relevant literature in CNKI,China Biology Medicine disc,VIP,Wanfang Data Knowledge Service Platform,PubMed,Web of Science,Embase,Cochrane Library and CINAHL from the database inception until December 16,2024.Two researchers independently screened and assessed the quality of the literature,obtained the necessary information,and a Meta-analysis of risk factors was conducted by using RevMan 5.4 software.Results 19 articles were included in total.Meta-analysis results showed that high body mass index,length of stay,smoking history,Eastern Cooperative Oncology Group(ECOG)score,granulocyte deficiency,neutropenia,Durie-Salmon stage,international staging system(ISS)stage and combined with diabetes,renal insufficiency,anemia,hypoalbuminemia were the risk factors for hospitalization infections in patients with MM after chemotherapy(P＜0.05).Conclusion This study provides a reference for intervening in the risk factors of hospitalization infections in MM patients after chemotherapy.Medical staff should prevent infections early based on relevant factors,identify high-risk populations,and maximize the protection of patient health outcomes and good prognosis.
