Research progress in targeted therapy and immunotherapy of metastatic colorectal cancer
10.12354/j.issn.1000-8179.2025.20250147
- VernacularTitle:转移性结直肠癌靶向治疗和免疫治疗的研究进展
- Author:
Wei CAIJIE
1
;
Tu WENYING
;
Li YUNXIA
;
Jian SHENGQIANG
;
Li WEN
;
Li HAILONG
;
Ren SHIPU
Author Information
1. 兰州石化总医院(甘肃中医药大学第四附属医院)(兰州市 730060)
- Publication Type:Journal Article
- Keywords:
colorectal cancer(CRC);
targeted therapy;
immunotherapy
- From:
Chinese Journal of Clinical Oncology
2025;52(8):420-426
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer(CRC)is a common malignancy of the digestive system,with increasing morbidity and mortality worldwide.The standard treatment for CRC has,in the past,been surgery,chemotherapy,and radiotherapy.However,these treatments have significant side effects and are particularly challenging for patients with advanced metastatic CRC(mCRC).Therefore,it is crucial to explore alternative and more effective treatments.In recent years,with the development of molecular technology,numerous biomarkers have been identified,and targeted therapy and immunotherapy have achieved surprisingly positive results in the treatment of mCRC.Patients receiving targeted ther-apy and immunotherapy have an improved prognosis and quality of life.On this basis,this article reviews the latest research progress in tar-geted therapy and immunotherapy for mCRC,providing a reference for precision treatment of mCRC.
