Epidemic Characteristics and Trend Prediction of Bladder Cancer Worldwide and in China:Based on the GLOBO-CAN 2022 Database
10.11735/j.issn.1004-0242.2025.07.A001
- VernacularTitle:全球及中国膀胱癌流行特征分析与趋势预测——基于GLOBOCAN 2022数据库
- Author:
Lingling LU
1
;
Yan SUN
1
;
Yongfeng YAN
1
;
Jian FAN
1
;
Jian ZHU
1
Author Information
1. 启东市人民医院/启东肝癌防治研究所/南通大学附属启东医院,江苏启东 226200
- Publication Type:Journal Article
- Keywords:
bladder cancer;
incidence;
mortality;
human development index;
global;
China
- From:
China Cancer
2025;34(7):499-506
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To analyze the incidence,mortality and trends of bladder cancer worldwide and in China in 2022.[Methods]The incidence and mortality data of bladder cancer were ob-tained from the GLOBOCAN 2022 database by geographical regions,sex,age,and human deve-lopment index(HDI).The crude incidence/mortality rate,age-standardized incidence/mortality rate(ASIR/ASMR)of bladder cancer were calculated.Simple linear regression and Spearman's correla-tion test were used to analyze the correlation between the HDI and ASIR/ASMR,the trends of in-cidence and projection in 2050 were estimated.[Results]In 2022,the estimated numbers of new cases and deaths of bladder cancer worldwide were 614 298 and 220 596,respectively,with ASIR and ASMR of 5.6/105 and 1.8/105.ASIR and ASMR in Europe were the highest,with 12.0/105 and 3.0/105,respectively.The ASIR and ASMR for males were higher than those for females,and increased rapidly after 40 years old of age.A positive correlation was observed between HDI levels and ASIR and ASMR of bladder cancer(r=0.670 and 0.434,respectively,both P＜0.001).It was projected that the global incidence and mortality of bladder cancer would reach 1.229 million and 0.494 million by 2050,and 0.176 million and 0.103 million for China,respectively.[Conclusion]The incidence and mortality of bladder cancer varies significantly among different region,sex,age and HDI levels worldwide.With the population aging and the industrialization accelerating,the risk of bladder cancer in China has been increasing.The prevention and control efforts for bladder cancer should be further strengthened.
