Risk factors analysis of osteoporosis combined with lumbar degenerative diseases in menopausal women
10.3969/j.issn.1673-9701.2025.18.009
- VernacularTitle:绝经期女性骨质疏松合并腰椎退行性病变的危险因素分析
- Author:
Binbin YAO
1
;
Jiahui YANG
1
Author Information
1. 台州市中心医院(台州学院附属医院)骨科,浙江台州 318000
- Publication Type:Journal Article
- Keywords:
Menopausal women;
Osteoporosis;
Lumbar degenerative disease;
Bone density;
Kyphosis deformity;
Beta C-terminal cross-linked telopeptides of type Ⅰ collagen
- From:
China Modern Doctor
2025;63(18):42-45,87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of osteoporosis combined with lumbar degenerative diseases in menopausal women.Methods A total of 108 menopausal women with osteoporosis treated at Taizhou Central Hospital were selected from November 2022 to November 2024.According to X-ray anteroposterior and lateral examinations,they were divided into study group(n=31)with lumbar degenerative lesions and control group(n=77)without.Logistic regression analyzed related factors,and receiver operating characteristic curve evaluated diagnostic values.Results Kyphosis,interleukin(IL)-17,beta C-terminal cross-linked telopeptides of type Ⅰ collagen(β-CTX)levels,and bone density T values were related factors(P＜0.05).Kyphosis deformity accounted for 64.52％,serum IL-17 with(142.71±18.23)pg/ml and serum β-CTX with(0.75±0.02)ng/ml in study group were higher than those in control group[38.96％,(129.63±15.46)pg/ml and(0.54±0.08)ng/ml],the T value of bone mineral density with(-3.94±0.28)was lower than that in control group with(-3.15±0.26),and there were statistical differences between two groups(P＜0.05).The combined diagnostic value of kyphosis,serum IL-17,β-CTX levels,and bone density T value is the highestt,with an area under the curve of 0.903(95％CI:0.854-0.952).Conclusion Kyphosis,serum IL-17,β-CTX levels and bone mineral density T value are all the influencing factors of osteoporosis combined with lumbar degenerative diseases in menopausal women,and the combined diagnosis value is the highest.
