Meta-analysis of the effect of early rehabilitation activities on diaphragm function in patients with mechanical ventilation
10.3969/j.issn.1673-9701.2025.18.006
- VernacularTitle:早期康复活动对机械通气患者膈肌功能影响的Meta分析
- Author:
Feifei HU
1
;
Fang WANG
;
Zhi WANG
;
Yao MING
Author Information
1. 成都中医药大学护理学院,四川成都 610075
- Publication Type:Journal Article
- Keywords:
Early rehabilitation activities;
Mechanical ventilation;
Diaphragm;
Meta-analysis
- From:
China Modern Doctor
2025;63(18):25-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the effect of early rehabilitation activities on diaphragm function in patients with mechanical ventilation.Methods Computerized system search databases included PubMed,Embase,Web of Science,Cochrane Library,China Biology Medicine disc,China National Knowledge Infrastructure,Wanfang Data Knowledge Service Platform,and VIP on the effects of early rehabilitation activities on diaphragm function in patients with mechanical ventilation.The search period was from the creation of the database to March 2025.Two researchers independently performed literature screening,literature quality evaluation,and data extraction.Results 9 papers,including 902 patients,were finally included.Meta-analysis showed that early rehabilitation activities improved diaphragm inspiratory thickness[standard mean difference(SMD)=0.67,95％CI:0.39-0.95,P＜0.000 01],diaphragm expiratory thickness(SMD=0.39,95％CI:0.16-0.63,P=0.0001),diaphragm thickness fraction(SMD=0.76,95％CI:0.58-0.94,P＜0.000 01)and diaphragm excursion(SMD=0.49,95％CI:0.27-0.72,P＜0.000 01),and reduced the incidence of patient failure to withdraw from the machine(relative risk=0.45,95％CI:0.31-0.65,P＜0.0001).Conclusion Early rehabilitation activities can improve diaphragm function in patients with mechanical ventilation,which has good clinical value and is worth standardized promotion and application in intensive care unit;The intervention strategy should be further refined in the future to improve the prevention and treatment strategy of diaphragm dysfunction.
