Clinical value of ultrasound-related indicators for kidney in predicting the occurrence of septic shock-induced acute kidney injury
10.3969/j.issn.1672-8270.2025.04.014
- VernacularTitle:肾脏超声相关指标预测脓毒症休克所致急性肾损伤发生的临床价值研究
- Author:
Lin PAN
1
;
Jiming LI
1
Author Information
1. 新疆医科大学第一附属医院急救中心重症监护室 乌鲁木齐 830000
- Publication Type:Journal Article
- Keywords:
Renal ultrasound;
Septic shock;
Renal hemodynamics;
Renal perfusion
- From:
China Medical Equipment
2025;22(4):69-73
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the differences of ultrasound on kidney in monitoring renal hemodynamics and renal perfusion of patients with septic shock-induced acute kidney injury(AKI),and the predictive value of ultrasound-related parameters on kidney for septic shock-induced AKI.Methods:This is a prospective study,a total of 100 patients with septic shock who were diagnosed and treated in our hospital between September 2022 and September 2023 were selected as the study subjects.They were divided into AKI group(35 cases)and non-AKI group(65 cases)according to the relative standards of＜Clinical Practice Guideline of Global Kidney Disease Prognosis for the Tissue of Acute Kidney Injury(2012)＞.The age,gender,body mass index(BMI),comorbidities,central venous pressure,serum creatinine,urea nitrogen,blood lactate,Acute Physiology And Chronic Health Evaluation II(APACHE II)score,and Sequential Organ Failure Assessment(SOFA)score of all patients were collected after they admitted to hospital.Ultrasound on kidney was used to detect the renal resistive index(RRI)and power Doppler ultrasound(PDU)scores for patients,and indicators included peak intensity(PI),mean transit time(MTT),and area under curve(AUCTC)of the time-intensity were collected.Results:After septic shock,the PI,AUCTC,MTT parameter and RRI score of AKI group were lower than those of non-AKI group,while the PUD score was higher than that of non-AKI group,and the differences of them between two groups were significant(t=5.391,8.978,5.664,2.626,5.102,P＜0.05).There were no significant differences in gender,age,BMI,comorbidities(diabetes,hypertension,coronary heart disease),blood lactate,APACHE II score,and SOFA score between the two groups(P＞0.05).After multiple confounding factors were rectified,the results showed that PI,AUCTC and PRI scores were independent influencing factors for occurring AKI in sepsis patients(OR=0.51,0.86,0.77,P＜0.05).The PI,AUCTC and RRI were used as continuous variable,and receiver operating characteristic(ROC)curve was used to analyze the predictive efficiency of PI,AUCTC and RRI for septic shock-induced AKI.The results indicated that the AUC values of PI,AUCTC and RRI were respectively 0.83(95%CI:0.75～0.91),0.79(95%CI:0.70～0.88)and 0.72(95%CI:0.62～0.82).Conclusion:Renal ultrasound-related indicators can effectively monitor renal hemodynamics and perfusion in patients with septic shock,and can further predict the risk of occurring AKI.It is suggested to promote that in clinical application.
