Case analysis of outbreak of Candida health care-associated infection based on database of global nosocomial infection outbreaks
10.11816/cn.ni.2025-248689
- VernacularTitle:基于全球医院感染暴发数据库的假丝酵母医院感染暴发案例分析
- Author:
Huishan CEN
1
;
Liang YAN
Author Information
1. 中山市人民医院医院感染管理科,广东中山 528400
- Publication Type:Journal Article
- Keywords:
Candida;
Nosocomial infection;
Outbreak;
Database of global nosocomial infection outbreaks
- From:
Chinese Journal of Nosocomiology
2025;35(5):782-787
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the worldwide outbreak incidents of Candida health care-associated infection so as to provide bases for clinical prevention and control of health care-associated infection.METHODS The data with the respect to outbreaks of Candida health care-associated infection from the database of global nosocomial in-fection outbreaks between its establishment and Mar.2024 were statistically analyzed.RESULTS There were 66 Candida outbreak incidents involving 22 regions,dominated by Europe and America.The worldwide outbreak inci-dents of Candida health care-associated infection generally showed a low prevalence and fluctuating upward trend.The outbreak incidents were highly prevalent in intensive care units(67.53％),with 15 department involved;neonatology department(27.27％),general surgery department(25.76％)and hematology/oncology department(16.67％)ranked the top 3.The young and middle-age adults(63.64％)and neonates(27.27％)were the major populations with predilections for the outbreak incidents,dominated by the population with bloodstream infection/sepsis(62.12％).The outbreak frequency of the non-Candida albicans was 81.82％,higher than 40.19％of the C.albicans.Healthcare workers(19.70％)and medical devices/instruments(15.15％)were the major infection sources.The major risk factors for the outbreaks included the bacterial carriers(48.48％),equipment contamina-ted with pathogens(24.24％),drugs contaminated with pathogens(21.21％).The transmission through contact(54.55％)was the major transmission route.Totally 12 items of prevention and control measures were taken for control of the outbreaks,including screening and surveillance,rigid implementation of hand hygiene,screening and surveillance of health care workers.CONCLUSIONS The outbreak incidents of Candida health care-associated infection are characterized by wide-range impact,various links involved,and great difficulties in prevention and control.It is necessary to formulate effective intervention measures based on the epidemiological characteristics of the outbreaks as early as possible so as to effectively prevent and control of the outbreaks.
