Progress in cancer therapy-related oral mucositis pathogenesis,diagnosis,and treatment
10.12354/j.issn.1000-8179.2025.20241110
- VernacularTitle:肿瘤治疗相关性口腔黏膜炎的发病机制和诊疗进展
- Author:
Hu FENGLIN
1
;
Wu GUOLIN
1
Author Information
1. 浙江大学医学院附属第一医院中医科(杭州市 310000)
- Publication Type:Journal Article
- Keywords:
cancer;
oral mucositis(OM);
prevention;
treatment
- From:
Chinese Journal of Clinical Oncology
2025;52(5):248-252
- CountryChina
- Language:Chinese
-
Abstract:
Oral mucositis(OM)is a prevalent and debilitating cancer therapy-related side effect that significantly impairs the quality of life of patients with cancer.In this article,we review anticancer treatment-induced OM,elucidate the underlying pathophysiological mechanisms,and discuss various preventive and therapeutic strategies,including basic oral care,nutritional supplements,cryotherapy,photobiomodula-tion therapy,and pharmacological interventions.While single modality treatments might yield certain clinical benefits,an integrated ap-proach,combining prophylactic measures with multimodal therapies,could more effectively reduce OM incidence and severity,promote mucosal healing,minimize the risk of serious complications,and enhance patient outcomes.
