Progress of exosomes in the development, diagnosis and treatment of cholangiocarcinoma
10.3760/cma.j.cn113884-20241023-00315
- VernacularTitle:外泌体在胆管细胞癌发生发展、诊断和治疗中的研究进展
- Author:
Qin YI
1
;
Zhekai WANG
;
Xietong MAO
;
Zuo MOU
;
Yuefeng ZHANG
Author Information
1. 武汉大学第一临床学院，武汉 430000
- Publication Type:Journal Article
- Keywords:
Cholangiocarcinoma;
Exosomes;
Tumor progression;
Tumor diagnosis;
Tumor treatment
- From:
Chinese Journal of Hepatobiliary Surgery
2025;31(7):552-556
- CountryChina
- Language:Chinese
-
Abstract:
Cholangiocarcinoma originates from bile duct epithelial cells. It has an insidious onset, a high degree of malignancy, a poor prognosis and a high recurrence rate. Exosomes are nanoscale vesicles with a bilayer membrane structure, containing abundant biomolecules such as DNA, RNA, proteins and lipids. Exosomes are important carriers for the exchange of substances and information between cells and are involved in a variety of pathophysiological processes. In addition, exosomes have great potential in the diagnosis and treatment of various diseases. This article reviews the role of exosomes in the occurrence and development of cholangiocarcinoma and their potential value in the diagnosis and treatment of cholangiocarcinoma.
