Progress in the application of blood purification therapy in the treatment of sepsis

VernacularTitle:血液净化在治疗脓毒症中的应用进展
Author: Qiuyuan XIA ¹ ; Guoyue LIU ; Miao CHEN
Author Information

1. 泸州市人民医院重症医学科,四川泸州 646000
Publication Type:Journal Article
Keywords: Sepsis; Blood purification therapy; Hemoperfusion; Plasma exchange
From: Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2024;31(6):746-750
CountryChina
Language:Chinese
Abstract: Sepsis is an organ dysfunction syndrome secondary to a host's dysfunctional response to infection.Its pathogenesis is complex,and inflammatory factors play an important role in its course.Sepsis has a high mortality and is difficult to treat.Clinicians are constantly exploring new treatment methods to reduce the fatality rate.Blood purification therapy is a developing auxiliary treatment method for sepsis.Blood purification therapies for sepsis include plasma exchange,continuous renal replacement therapy,and hemoperfusion.Though operating through different mechanisms-removing cytokines,endotoxins,or pathogens-these therapies share the goal of improving patient outcomes.This article aims to summarize the application progress of various blood purification methods in the treatment of sepsis,in order to clarify the effectiveness of blood purification therapy in infectious diseases.However,the specific implementation timing and frequency still need further exploration,laying a foundation for subsequent research.