Theoretical analysis and clinical application of"blood syndrome of sepsis"
10.3969/j.issn.1008-9691.2024.06.021
- VernacularTitle:脓毒症血分证的理论辨析与临床应用
- Author:
Linqin MA
1
;
Yi LIU
;
Hui ZHANG
;
Junxi LIU
;
Caijun WU
Author Information
1. 北京中医药大学东直门医院急诊科,北京 100700;北京中医药大学脓毒症研究所,北京 100700
- Publication Type:Journal Article
- Keywords:
Sepsis;
Blood syndrome;
Theoretical exploration;
Vascular endothelial injury
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2024;31(6):751-755
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis poses a major threat to human health due to its high morbidity and mortality.At present,there are still limitations to the comprehensive intervention plan for sepsis.Especially when sepsis progresses to the stage of septic shock,multiple organ dysfunction syndrome(MODS)or disseminated intravascular coagulation(DIC)and other critical conditions,there are no effective specific treatment methods,which makes sepsis a more severe syndrome.Traditional Chinese medicine has special advantages in participating in intervention and treatment of sepsis due to its holistic concept,syndrome differentiation and other treatment theories.Therefore,our team proposed to summarize the characteristics of traditional Chinese medicine syndrome in the critical stage of sepsis with the concept of"blood syndrome of sepsis",based on traditional Chinese medicine syndrome differentiation theoretical system and clinical experience summary.In this article,we summarized the modern research progress of the blood syndrome of sepsis from the perspectives of its pathogenesis and basic research.And we summarized its main clinical symptoms,explored its diagnosis and differential diagnosis from the perspective of conceptual analysis,and outlined and discussed the effective treatment principles and commonly used traditional Chinese medicine for this syndrome.It should be noted that endothelial injury plays an important role in the objective mechanism of blood syndrome of sepsis.The traditional Chinese medicine treatment with cooling blood and promoting blood circulation as the core principle may have a therapeutic effect on blood syndrome of sepsis through the protection of vascular endothelial function,and curb the trend of sepsis progressing to critical conditions such as shock,MODS,and DIC,ultimately improving the efficacy and prognosis of sepsis patients.We hope that our thinking and discussion could provide reference for the early identification and early treatment in the critical stage of sepsis,based on the theory of traditional Chinese medicine.
