Obesity related pancreatic cancer:potential therapeutic transformation opportunities
10.3781/j.issn.1000-7431.2024.2407-0445
- VernacularTitle:肥胖相关胰腺癌:潜在的治疗转化机遇
- Author:
Jinfan ZHANG
1
;
Guangfu WANG
;
Huijuan WANG
;
Cheng LI
;
Kuirong JIANG
;
Yi MIAO
;
Wentao GAO
;
Zipeng LU
Author Information
1. 南京医科大学第一附属医院胰腺中心,江苏 南京 210029
- Publication Type:Journal Article
- Keywords:
Pancreatic cancer;
Obesity;
Pathogenesis
- From:
Tumor
2024;44(12):1180-1190
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is a highly malignant digestive system tumor with poor prognosis.Its incidence is closely related to the level of regional development.Epidemiology shows that with the progress of urbanization,the proportion of obese people in the world is increasing over the years.Meanwhile,obesity has also been found to be one of the risk factors for pancreatic cancer.However,the mechanism of obesity regulating pancreatic cancer is still unclear at present.Researches show that obese people with pancreatic cancers have different tumor pathological mechanisms and higher risk of surgical complications.Therefore,this article will review the potential transformation mechanism between microscopic pathological changes and clinical manifestations of obesity related pancreatic cancer.
