VernacularTitle:肿瘤微环境"冷热转换":细胞电池(Tesla Cell)
Author: Yingting LIU ¹ ; Weidong HAN ; Jingting JIANG
Author Information

1. 苏州大学附属第三医院肿瘤生物诊疗中心江苏省肿瘤免疫治疗工程技术研究中心细胞治疗研究院,江苏常州 213003
Publication Type:Journal Article
Keywords: Tesla cell; cold tumor; hot tumor; tumor microenvironment(TME); immunotherapy
From: Chinese Journal of Cancer Biotherapy 2024;31(12):1167-1177
CountryChina
Language:Chinese
Abstract: Immunotherapy has provided new approaches for tumor treatment.The immune status within the tumor microenvironment of cancer patients,characterized as"cold"or"hot",determines whether they will respond to immunotherapy.This article innovatively proposes the concept of"cell batteries(or Tesla Cell)"to promote the"cold-hot switch"of the tumor microenvironment.It reviews the current research status and progress in tumor immunotherapy,focusing on the concepts of"cold tumors"and"hot tumors,"the conversion strategies between them,as well as the types and applications of"Tesla cell",aiming to provide a theoretical foundation for the development of new immunotherapeutic strategies for tumors.