Numerical simulation technique for predicting effect of self-expanding prosthetic valve stents for treating type 0 bicuspid aortic valve stenosis
10.13929/j.issn.1003-3289.2025.01.028
- VernacularTitle:数值模拟技术预测自膨式人工瓣膜支架治疗0型二叶主动脉瓣狭窄效果
- Author:
Jiachen DU
1
;
Hongtao XU
;
Qingqi HAN
;
Guomin CUI
Author Information
1. 上海理工大学能源与动力工程学院,上海 200093
- Publication Type:Journal Article
- Keywords:
bicuspid aortic valve;
finite element analysis;
stents
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):133-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of numerical simulation technique for predicting effect of self-expanding prosthetic valve(SEV)stents for treating type 0 bicuspid aortic valve(BAV)stenosis with different implantation strategies.Methods Based on CT angiography data from a patient with type 0 BAV stenosis and asymmetric calcification,three-dimensional models of aortic root wall,aortic valve calcification,native valve and SEV were reconstructed.ABAQUS/Explicit dynamic analysis module was used to observe the interaction between SEV stents and aortic root including root stress and stent deformation under different implantation strategies(implantation depths of high,medium or low,and implantation centers of central or eccentric position).Results When SEV was implanted centrally at low depth and central position,the Von Mises stress on aortic root wall was the highest,with mean and peak value of 2.28 and 45.30 kPa,respectively.When SEV was implanted at medium depth and central position,the average eccentricity of stent across all planes was the highest(0.254),while when implanted at high depth and eccentric position,the average ellipticity in planes S1-S3 was the minimal(0.124).Conclusion Different SEV implantation strategies resulted in varying interactions between stent and aortic root.Numerical simulation technique could be used to determine the implantation center and depth based on the size and location of type 0 BAV calcification,which was helpful to reducing rupture risk of aortic annulus,increasing durability and improving prognosis of SEV stent.