Correlation between visceral fat area and triglyceride-glucose index in people with normal body mass index based on quantitative CT
10.13929/j.issn.1003-3289.2025.01.022
- VernacularTitle:基于定量CT分析正常体质量指数人群内脏脂肪面积与甘油三酯-葡萄糖指数的相关性
- Author:
Xin LI
1
;
Yang ZHOU
;
Zhi ZOU
;
Jing ZHOU
;
Xiaolin ZHANG
;
Min QU
;
Hao LI
;
Yongli LI
Author Information
1. 河南大学人民医院医学影像科,河南郑州 450003
- Publication Type:Journal Article
- Keywords:
body composition;
adipose tissue;
tomography,X-ray computed;
triglyceride-glucose index
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):104-108
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between visceral fat area(VFA)and triglyceride-glucose(TyG)index in people with normal body mass index(BMI)based on quantitative CT(QCT).Methods Totally 1 358 healthy adults with normal BMI who underwent QCT body composition measurement were retrospectively enrolled and divided into normal visceral fat group(normal group,VFA＜100 cm2,n=509),mild visceral fat accumulation group(mild group,100 cmn2≤VFA＜150 cm2,n=431)and severe visceral fat accumulation group(severe group,VFA≥150 cm2,n=418)according to VFA measured with QCT.Pearson and Spearman correlation analysis were performed to observe correlations of TyG index with general data and body composition in 20-40,41-60,61-90 years old men and women with normal BMI,respectively.Multiple linear regression analysis was performed to screen the independent impact factors of TyG index in normal BMI people.Results Low density lipoprotein cholesterol(LDL-C),total cholesterol(TC),glutamic-pyruvic transaminase(GPT),VFA and subcutaneous fat area(SFA)of men with normal BMI at different age stages were weakly-lowly positively correlated with TyG index(r=0.143-0.459,all P＜0.05),while high-density lipoprotein cholesterol(HDL-C)were weakly-lowly negatively correlated with TyG index(r=-0.410--0.222,all P＜0.05).LDL-C,VFA and SFA of women with normal BMI at different age stages were weakly-lowly positively correlated with TyG index(r=0.206-0.495,all P＜0.05).GPT,TC,VFA and liver fat content(LFC)were all independent risk factors,while HDL-C was independent protective factor for TyG index in people with normal BMI(all P＜0.05).Conclusion VFA was positively correlated with TyG index in people with normal BMI.Measurement of abdominal body composition based on QCT combined with lipid indexes had certain potential for predicting insulin resistance and relative metabolic diseases in abdominal obese people.
