131I whole-body scanning and 131I-SPECT/CT for evaluating differentiated thyroid cancer after operation and initial radioactive iodine treatment
10.13929/j.issn.1003-3289.2025.01.014
- VernacularTitle:131I-全身平面显像与131I-SPECT/CT评估术后首次放射性碘治疗后分化型甲状腺癌
- Author:
Huan XI
1
;
Lin LIN
1
;
Rong FAN
1
;
Ke YANG
1
;
Zhengmao WEI
1
;
Yiqing ZHENG
1
;
Xuejuan WANG
1
;
Rong ZHENG
1
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院核医学科,北京 100021
- Publication Type:Journal Article
- Keywords:
thyroid neoplasms;
cell differentiation;
iodine radioisotopes;
tomography,emission-computed,single-pho ton
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):65-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To comparatively observe the value of 131I whole-body scanning(WBS)and 131I-SPECT/CT for evaluating residual thyroid tissue,lymph node and distant metastasis,as well as risk of recurrence of differentiated thyroid cancer(DTC)after surgical resection and initial radioactive iodine(RAI)treatment.Methods Totally 367 DTC patients who underwent initial RAI treatment after surgical resection and then 131I-WBS and 131I SPECT/CT scanning were retrospectively collected.131I-WBS and 131I SPECT/CT were compared for identifying residual thyroid,lymph node and distant metastases.According to follow-up results,the risk of DTC recurrence was evaluated based on 131I-WBS and 131I-SPECT/CT,respectively.Results Residual thyroid was detected in 353 cases and suspected in 3 cases with 131 I-WBS,which was diagnosed in 349 cases with 131I-SPECT/CT,and no significant difference was found between 2 methods(P=0.289).131I-WBS detected 36 cases with and suspected 67 cases with lymph node metastases,312 without distant metastases,while 131I-SPECT/CT diagnosed lymph node metastases in 52 cases;131I-WBS detected 20 cases with and suspected 35 cases with distant metastases,while 131I-SPECT/CT diagnosed 60 cases with distant metastases but could not diagnose in 3 cases,304 without distant metastases.The detection rate of 131I-SPECT/CT for lymph node and distant metastasis were both higher than that of 131I-WBS(P=0.018,P＜0.001).During follow-up period,there were 94 cases with low risk,155 with medium risk and 118 with high risk of DTC recurrence according to 131I-SPECT/CT,while 116 cases of low risk,137 of medium risk and 114 of high risk based on 131I-SPECT/CT,and the evaluating results were different between 2 methods in 40 cases(40/367,10.90％).Conclusion Compared with 131I-WBS,131I-SPECT/CT had better clinical value for evaluating lymph node and distant metastases and assessing recurrence risk of DTC after initial RAI treatment.
