CT angiography radiomics for evaluating risk of basilar tip aneurysm rupture
10.13929/j.issn.1003-3289.2025.01.005
- VernacularTitle:CT血管造影影像组学评估基底动脉尖动脉瘤破裂风险
- Author:
Song LIU
1
;
Chao TIAN
;
Tao REN
;
Chen CAO
;
Song JIN
;
Shuang XIA
Author Information
1. 天津医科大学一中心临床学院,天津 300191;天津市环湖医院医学影像科,天津 300350
- Publication Type:Journal Article
- Keywords:
aneurysm,ruptured;
tomography,X-ray computed;
machine learning;
radiomics
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):20-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of CT angiography(CTA)radiomics for evaluating the risk of basilar tip aneurysm(BTA)rupture.Methods Totally 133 BTA patients were retrospectively enrolled and divided into ruptured group(n=39)and unruptured group(n=94)based on BT A ruptured or not,also divided into training set(n=93)and test set(n=40)at the ratio of 7∶3.CTA radiomics features of BTA were extracted,the best radiomics features were screened,and the radiomics score(Radscore)was calculated.Then machine learning(ML)models were established with logistic regression(LR),random forest(RF),decision tree(DT)and K-nearest neighbor(KNN)algorithms,respectively.Radscore model was also established,and finally a combined model was constructed based on clinical data,routine imaging findings and Radscore.The efficacy of the above models for evaluating the risk of BTA rupture were comparatively analyzed.Results Finally 4 radiomics features of BTA were obtained.The area under the curve(AUC)of LR,RF,DT and KNN radiomics models for differentiating ruptured and unruptured BTA in training set was 0.770,0.816,0.817 and 0.795,respectively,while that in test set was 0.795,0.793,0.786 and 0.824,respectively,both being not significant different(both P＞0.05).Patient's gender,alcohol consumption history,BTA morphology and Radscore were all independent impact factors of BT A rupture(all P＜0.05),which were used to establish a clinical-routine imaging model.For all 133 cases,AUC of the combination model for differentiating ruptured and unruptured BTA was 0.877,of Radscore model was 0.775,while that of clinical-routine imaging model was 0.677,of the former was significantly higher than of the last two(both P＜0.05).Conclusion CTA radiomics was helpful for evaluating the risk of BTA rupture.Combining with clinical data and routine imaging findings could further improve the value of CTA radiomics.
