Expert consensus on renally inappropriate medication for the elderly in China(2025 edition)

VernacularTitle:老年人肾脏不适当用药目录中国专家共识(2025版)
Author: Chen LI ¹ ; Qiangguo AO ; Mengli CHEN
Author Information

1. 解放军总医院药剂科，北京　100853
Publication Type:Journal Article
Keywords: Non-rational use of drug; Renal toxicity; Catalogs, drug; Expert consensus
From: Chinese Journal of Geriatrics 2025;44(6):691-701
CountryChina
Language:Chinese
Abstract: Renally inappropriate medication (RIM)refers to the administration of drugs without proper dosage adjustment based on renal function or the use of contraindicated agents, primarily including nephrotoxic agents and renally excreted medications.Such practices may accelerate disease progression and increase the risk of adverse drug events, posing a significant burden on China's healthcare system.Early identification and intervention for RIM in elderly patients provide critical opportunities to mitigate the decline in abnormal renal function.Currently, there is a lack of specific, actionable guidelines for preventing RIM in elderly patients with chronic kidney disease(CKD)in China.This expert consensus systematically reviews evidence-based medical literature from domestic and international studies over the past two decades, integrates expertise and clinical insights from geriatric medicine and clinical pharmacology specialists to establish practical recommendations for preventing RIM in elderly patients with CKD.