Predictive value of CNPVSS on the curative effect of rehabilitation treatment combined with hyperbaric oxygen for patients with chronic disorder of consciousness
10.3760/cma.j.cn311847-20190818-00206
- VernacularTitle:中国南京持续植物状态量表对高压氧综合康复治疗长期意识障碍患者疗效的预评估价值
- Author:
Zhiqiang GAO
1
;
Yafeng LIU
1
;
Yuliang QI
1
;
Xingming PAN
1
;
Jirong GAO
1
;
Aiping WANG
1
;
Hulong MA
1
;
Xiangrong PEN
1
;
Tingting XU
1
;
Xia WANG
1
Author Information
1. 211100 南京，南京紫金医院
- Publication Type:Journal Article
- Keywords:
China Nanjing persistent vegetative state scale;
Hyperbaric oxygen;
Disorder of consciousness;
EEG;
EPs
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2020;27(4):489-492
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of China Nanjing persistent vegetative state scale (CNPVSS) on the curative effect of the patients with chronic disorder of consciousness, by analyzing the curative effect of the rehabilitation treatment combined with hyperbaric oxygen (HBO) for patients with chronic disorder of consciousness.Methods:A total of 48 patients with chronic disorder of consciousness admitted to Nanjing Zijin Hospital to receive rehabilitation treatment combined with HBO from the September of 2016 to the May of 2019 were selected according with the analytical criteria. Before the treatment, the patients were evaluated by CNPVSS and received electroencephalogram (EEG) and evoked potentials (EPs) examinations. The patients′ consciousness was evaluated again before discharge, the results of CNPVSS and electrophysiological examinations were recorded, and the correlation between the results and the changes of the consciousness was analyzed statistically.Results:The results of CNPVSS was positive correlated with near-term curative effect ( r=0.401, P=0.005); the rate of awakening after treatment was 46.2% among those who were scored as minimally conscious state (MCS) by CNPVSS; the rate of awakening after treatment was 17.1% among those who were at vegetative state (VS) or in a coma; the rate of awakening after treatment of the MCS patients was higher than those of the patients at VS or in a coma ( χ2=4.255, P=0.039). The recordings of right somatosensory evoked potentials (SSEPs) N20 was positive correlated with curative effect ( r=0.312, P=0.031); and the left visual evoked potentials (VEPs) V100 was positive correlated with curative effect ( r=0.285, P=0.049). There were no statistical significance found between other electrophysiological recordings with curative effect. Conclusion:CNPVSS can be an important tool to predict the outcome of the rehabilitation treatment combined with HBO for the patients with chronic disorder of consciousness, and the recordings of SSEPs and VEPs also are of a certain reference value in predicting the prognosis.
