Research progress of combined Chinese and western medicine in the treatment of diabetic ketoacidosis
10.3969/j.issn.1008-9691.2024.05.020
- VernacularTitle:中西医结合治疗糖尿病酮症酸中毒的研究进展
- Author:
Huilan LIU
1
;
Yanguo FENG
1
Author Information
1. 解放军联勤保障部队第九八五医院中医内分泌科,山西太原 030000
- Publication Type:Journal Article
- Keywords:
Combined Chinese and western medicine;
Diabetic ketoacidosis;
Research progress
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2024;31(5):630-633
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic ketoacidosis (DKA) is the most serious acute complication of diabetes mellitus,characterized by rapid onset and progression,which can lead to coma or even lead to death in severe cases. Modern pharmacological studies have shown that some traditional Chinese medicines have the efficacy of inhibiting glycogenolysis,attenuating pancreatic β-cell damage,improving pancreatic β-cell function,and alleviating the obstruction of insulin signalling,which can effectively reduce hyperglycemia and hyperinsulinemia in diabetic mice,as well as improve insulin resistance and other symptoms. At present,the clinical treatment of DKA based on insulin and combined with the use of traditional Chinese medicines,such as clearing heat and diarrhoeing fire to detoxify,benefiting qi and nourishing yin to nourish blood,cooling blood and activate blood circulation to remove blood stasis,strengthening the spleen and the stomach to warm the yang,etc.,can control the condition rapidly,alleviate the symptoms,lower the blood glucose,promote the disappearance of ketones and correct the acidosis,and it can also reduce the dosage of insulin,thus reducing the duration of the disease. This article reviews the literature on the pathogenesis and main treatment options for DKA in western medicine,the etiology and mechanisms of DKA in traditional Chinese medicine,as well as Chinese medicine treatments and prescriptions. The aim is to highlight the advantages of traditional Chinese medicine and provide valuable references for the clinical management of DKA.
