Ultrasound four-dimensional auto left atrial quantification technique for evaluating changes of left atrial volume and function in ankylosing spondylitis patients with different activity
10.13929/j.issn.1003-3289.2024.12.008
- VernacularTitle:超声四维自动左心房定量技术评价不同疾病活动度强直性脊柱炎患者左心房容积及功能改变
- Author:
Siliang LI
1
;
Jianjun YUAN
1
;
Xijun ZHANG
1
;
Yu LU
1
;
Haohui ZHU
1
Author Information
1. 河南省人民医院超声科,河南郑州 450003
- Publication Type:Journal Article
- Keywords:
spondylitis,ankylosing;
echocardiography,four-dimensional;
atrial function,left
- From:
Chinese Journal of Medical Imaging Technology
2024;40(12):1842-1846
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore changes of left atrial(LA)volume and function in ankylosing spondylitis(AS)patients with different activity by using ultrasound four-dimensional auto LA quantification(4D Auto LAQ)technique.Methods Eighty-nine AS patients were retrospectively selected and divided into remission group(group A,n=20),low activity group(group B,n=25),high activity group(group C,n=23)and very high activity group(group D,n=21)according to AS disease activity score-C reactive protein(ASDAS-CRP).Meanwhile,54 healthy adults with age and gender matched were recruited as control group.Conventional echocardiographic parameters and LA volume and strain parameters obtained with 4D Auto LAQ technique were compared among groups.Multiple ordinal logistic regression was used to analyze the correlations of LA volume and strain parameters with AS disease activity.Results The ratio of early diastolic peak flow velocity of mitral orifice to early diastolic velocity of lateral mitral annulus(E/e')and LA minimum volume(LAVmin),the maximum volume(LAVmax),presystolic volume(LAVpre),ejection fraction(LAEF),active ejection fraction(LAaEF)and passive ejection fraction(LApEF)were all significantly different among groups,so were LA longitudinal strain during reservoir phase(LASr-l),conduit phase(LAScd-l),contraction phase(LASct-l)and circumferential strain during reservoir phase(LASr-c),conduit phase(LAScd-c)and contraction phase(LASct-c)(all P＜0.001).LAVmin was positively correlated(OR=7.106,B=1.96),while LASr-l and LASct-l were negatively correlated with AS activity(OR=0.235,0.145,B=-1.44,-1.93).Conclusion With the increase of disease activity,LAVmin in AS patients gradually increased,while LASr-l and LASct-l gradually decreased.
