Metabolic characteristics of lymphomas with Chinese experts grade Ⅰ recommendation for examination of 18F-FDG PET/CT guideline
10.13929/j.issn.1003-3289.2024.12.027
- VernacularTitle:指南内中国专家Ⅰ级推荐行18F-FDG PET/CT检查淋巴瘤代谢特点
- Author:
Qichen JIA
1
;
Jing BAI
;
Zhihua ZHANG
;
Yu GAO
;
Liying WU
;
Aihui WANG
Author Information
1. 承德医学院附属医院核医学科,河北承德 067000
- Publication Type:Journal Article
- Keywords:
lymphoma;
positron-emission tomography and computed tomography;
fluorodeoxyglucose F18
- From:
Chinese Journal of Medical Imaging Technology
2024;40(12):1936-1940
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the metabolic characteristics of lymphomas with Chinese experts grade Ⅰrecommendation for examination of 18F-FDG PET/CT guideline.Methods Totally 115 patients with lymphoma who underwent baseline 18F-FDG PET/CT were retrospectively enrolled and divided into grade Ⅰ A group(n=69,lymphomas with international experts grade Ⅰ recommendation,including Hodgkin lymphoma[HL]and diffuse large big cell lymphoma[DLBCL]),grade Ⅰ B group(n=26,lymphomas with Chinese experts grade Ⅰ recommendation,including peripheral T-cell lymphoma[PTCL],primary mediastinal large B-cell lymphoma[PMBL],Burkitt lymphoma[BL],high-grade follicular lymphoma[FL]and lymphoblastic leukemia/lymphoma)and grade Ⅱ group(n=20,lymphomas with international experts grade Ⅱ recommendation,including marginal zone lymphoma[MZL],mantle cell lymphoma[MCL],low-grade FL and non-gastric mucosa-associated lymphoma tissue lymphoma[MALToma]).PET/CT parameters were compared among 3 groups and between each 2 groups.Results Significant differences of the maximum standard uptake value(SUVmax),the mean standard uptake value,peak standard uptake value,the maximum standard uptake value normalized by lean body mass,the mean standard uptake value normalized by lean body mass,peak standard uptake value normalized by lean body mass,lesion/liver SUVmax and lesions/mediastinum SUVmax were found among 3 groups(all P<0.05),also between grade Ⅱ group and each of the other 2 groups(both P<0.05).Conclusion Lymphomas with Chinese experts grade Ⅰ recommendation for examination of 18F-FDG PET/CT guideline presented high metabolism on 18F-FDG PET/CT,similar to HL and DLBCL but higher than MZL,MCL,low-grade FL and non-gastric MALToma.