Advances in managing sepsis-associated gastrointestinal dysfunction using Batri-7:insights from traditional Mongolian medicine
10.3969/j.issn.1008-9691.2024.05.021
- VernacularTitle:蒙药巴特日-7治疗脓毒症胃肠功能障碍的研究进展
- Author:
Gele QING
1
;
Yunbilige WU
;
Tejin BA
;
Bagenna BAO
;
Hao HAO
Author Information
1. 内蒙古自治区国际蒙医医院急诊与重症医学科,内蒙古自治区呼和浩特 010010
- Publication Type:Journal Article
- Keywords:
Sepsis;
Intestinal mucosal barrier function;
Mongolian medicine Bateri-7
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2024;31(5):634-637
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is one of the common diseases in the intensive care unit (ICU),and its pathophysiological mechanism is characterized by a dysregulated host response to infection leading to multiple organ dysfunction. Statistical data indicate that approximately 20.6％ of ICU patients have sepsis. Sepsis is prone to cause gastrointestinal dysfunction and acute damage to organs such as the lungs,heart,and kidneys. During sepsis,the intestinal mucosal barrier,as an essential component of normal intestinal physiological function,effectively prevents harmful pathogens from entering the organs and the bloodstream,thereby reducing the risk of organ damage associated with sepsis. However,due to this vulnerability,the intestine also becomes one of the first organs attacked by bacteria and viruses. Therefore,maintaining the integrity of the intestinal mucosal barrier is crucial for improving the absorption of enteral nutrients in patients with severe sepsis and enhancing their ability against microbial entry into the bloodstream,thereby inhibiting the progression of sepsis,which carries significant clinical importance. The Mongolian medicine Bateri-7 is a commonly used formula in Mongolian hospitals in Inner Mongolia Autonomous Region,known for its antibacterial properties,and is applied in the treatment of inflammatory diseases such as enteritis and pneumonia. This medication is routinely used in our hospital's department of emergency and critical care medicine for treating gastrointestinal dysfunction in sepsis,severe pneumonia,and other intestinal inflammatory diseases. This paper will focus on discussing the definition of sepsis,its pathogenesis,the function of the intestinal barrier,and the therapeutic and protective effects of Mongolian medicine Bateri-7 in addressing intestinal barrier dysfunction in sepsis patients,providing theoretical support for the clinical application of Bateri-7.
