Evaluation on the Efficacy and Advantages and Mechanisms of TCM in Preventing and Treating"Inflammation-cancer Transformation"of Colorectal Adenoma-colorectal Cancer
10.19879/j.cnki.1005-5304.202401278
- VernacularTitle:中医药防治结直肠腺瘤-结直肠癌"炎-癌转化"疗效、优势评价及作用机制
- Author:
Xiaojuan TANG
1
;
Yuan REN
;
Min HE
;
Liang ZHAO
;
Yuan LYU
;
Yongmin LI
;
Jing HUANG
;
Yongheng HE
Author Information
1. 湖南省中西医结合医院(湖南省中医药研究院附属医院),湖南省中医药研究院,湖南 长沙 410006
- Publication Type:Journal Article
- Keywords:
TCM;
colorectal adenoma-colorectal cancer;
inflammation-cancer transformation;
advantage evaluation;
mechanism
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(2):20-24
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal adenoma is a definite precancerous lesion,and the"inflammation-cancer transformation"is a key pathological link in the process of colorectal adenoma-cancer evolution.Under the guidance of the theory of"preventive treatment of diseases"in TCM,prevention before disease onset and preventing the development of the occurred disease has become the consensus and the important subject of clinical research to block the"inflammation-cancer transformation"and prevent the precancerous lesions of colorectal cancer.This article discussed the effectiveness of TCM in preventing and treating the"inflammation-cancer transformation"from different aspects.Its advantages are reflected in improving the symptoms of TCM and improving the quality of life,etc.Its mechanism may be related to inhibiting the activation of cancer-promoting signals,regulating inflammation,maintaining intestinal microbial homeostasis,and protecting the intestinal barrier.By explaining the pathogenesis of adenoma-cancer transformation in TCM,this article discussed the efficacy and advantages of TCM to block"inflammation-cancer transformation",analyzed its intervention targets and pathways,providing references for the intervention of TCM in the management of precancerous lesions of colorectal cancer and the synergistic prevention and treatment of traditional Chinese and Western medicine.
