Study on the Distribution of TCM Syndromes of Severe Mycoplasma Pneumoniae Pneumonia in Children Based on Factor Analysis and Clustering Analysis
10.19879/j.cnki.1005-5304.202407378
- VernacularTitle:基于因子分析和聚类分析的儿童重症肺炎支原体肺炎中医证候分布研究
- Author:
Fengye JI
1
;
Zhongyi ZHU
;
Jin ZHANG
;
Ling WANG
;
Yan YANG
Author Information
1. 北京中医药大学东直门医院,北京 100700
- Publication Type:Journal Article
- Keywords:
severe mycoplasma pneumoniae pneumonia;
TCM syndromes;
factor analysis;
clustering analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(2):144-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distribution law of TCM syndromes in children with severe mycoplasma pneumoniae pneumonia(SMPP)based on factor analysis and clustering analysis;To provide references for accurately identifying this disease.Methods General data,symptoms,signs and tongue and pulse were retrospectively collected from 408 children with SMPP who were hospitalized in the Department of Traditional Chinese Medicine of Beijing Children's Hospital,Capital Medical University between September 2019 and November 2023.The relevant clinical information was extracted and entered into the Excel 2019 database,and SPSS 27.0 was used to perform factor analysis.The sample of 408 cases was subjected to K-means clustering analysis,and finally,the distribution of TCM syndromes was derived.Results Factor analysis screened five common factors with eigenvalue>1,and its cumulative contribution rate was 63.063%;clustering analysis co-classified four types of syndromes,among which phlegm-heat-closure lung syndrome,toxic-heat-closure lung syndrome,lung-spleen-qi deficiency syndrome and healthy qi deficiency and pathogens attachment syndrome accounted for 39.22%,32.35%,15.20%and 12.75%,respectively.Conclusion Pediatric SMPP is characterized by toxic heat,qi deficiency,phlegm-heat,damp-heat and yin deficiency,and the disease is located in lungs,spleen and heart;TCM syndromes are characterized by phlegm-heat-closure lung,toxic-heat-closure lung,healthy qi deficiency and pathogens attachment and lung-spleen-qi deficiency,with phlegm-heat-closure lung syndrome and toxic-heat-closure lung syndrome being the most common syndromes.
