Imaging longitudinal study of coronary artery plaques in elderly men with coronary artery disease and myocardial bridges
10.3969/j.issn.1009-0126.2025.02.011
- VernacularTitle:老年男性冠心病患者合并心肌桥冠状动脉斑块的影像学纵向研究
- Author:
Xue ZHENG
1
;
Jinjin CUI
1
;
Xinjiang WANG
1
;
Guanzhong LIU
1
;
Bingqi KANG
1
;
Peng TIAN
1
;
Hongxiang YAO
1
Author Information
1. 100853 北京,解放军总医院第二医学中心放射诊断科国家老年疾病临床医学研究中心
- Publication Type:Journal Article
- Keywords:
myocardial bridging;
coronary disease;
adipose tissue;
longitudinal studies
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(2):173-177
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the longitudinal imaging features of coronary artery plaques in elderly male patients with CHD and myocardial bridges and explore the longitudinal changing pat-terns.Methods A total of 117 elderly male CHD patients who underwent two examinations of coronary computed tomography angiography in our medical center from January 2018 to Septem-ber 2023 were enrolled in this study.Then 216 small plaques(0.1-50 mm3 in size)were subjec-ted,and classified into the proximal myocardial bridge group(98 plaques)and other heart part group(118 plaques)according to the site of the plaques.Plaque volume,plaque composition vol-ume,FAI,and CT-derived fraction flow reserve(CT-FFR)were calculated and recorded.Results In the 2 groups of plaques,there were no statistically differences in the plaque length,plaque nec-rotic core volume,and FAI derived from the second examination than the baseline one(P＞0.05).The plaque volume,intra-plaque fibers,and dense calcified volume of plaques in the second exami-nation were significantly greater than those at baseline,and CT-FFR was obviously smaller than the baseline level in both groups(P＜0.05,P＜0.01).In the proximal myocardial bridge group,the intra-plaque fibrofat volume in the second examination was significantly larger than that of baseline,while opposite phenomenon was observed in the plaques of the other heart part group(P＜0.05).The annual changing rates of intraplaque fibrofat volume and FAI were significantly higher in the proximal myocardial bridge group than the other heart part group[0.51％(-0.32％,0.51％)vs 0.02％(-0.46％,0.20％),P=0.046;0.55％(-2.44％,1.76％)vs 0.33％(-1.36％,2.63％),P=0.044].Conclusion In elderly male patients,the intraplaque fibrofat vol-ume,FAI and CT-FFR are more likely to change in the proximal plaques of the left anterior de-scending artery myocardial bridge than the plaques of other parts of heart,so the proximal plaques of the left anterior descending artery need more clinical attention and early intervention.
