Correlation between triglyceride glucose index and prognosis in elderly patients with unstable angina
10.3969/j.issn.1009-0126.2025.02.003
- VernacularTitle:三酰甘油葡萄糖乘积指数与老年不稳定性心绞痛患者预后的关系
- Author:
Xiang ZHOU
1
;
Ruihan LIU
1
;
Yutong LIU
1
;
Fan TIAN
1
;
Jie ZHANG
1
;
Xiaomao WANG
1
;
Jian CAO
1
Author Information
1. 100853 北京,解放军总医院第二医学中心保健四科国家老年疾病临床医学研究中心
- Publication Type:Journal Article
- Keywords:
angina,unstable;
percutaneous coronary intervention;
prognosis;
regression analysis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(2):136-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between triglyceride glucose(TyG)index and per-cutaneous coronary intervention(PCI)following drug treatment in elderly patients with unstable angina pectoris(UAP).Methods A total of 221 elderly UAP patients admitted to the Hyperbaric Oxygen Department of the First Medical Center of Chinese PLA General Hospital from March 2016 to March 2024 were enrolled,and based on the tertiles of the TyG index,they were divided into low,medium and high TyG index groups(the index:≤8.48,8.49-8.92,＞8.92;with 74,74 and 73 cases,respectively).Clinical data of all patients were collected,and whether undergoing PCI after discharge was defined as the endpoint event.The follow-up ended on May 10,2024.The clini-cal data were compared in the three groups.Kaplan-Meier survival curves were plotted to compare the survival rates among the groups,and Cox proportional hazards regression model was em-ployed to analyze the influencing factors for occurrence of endpoint event.Results There were significant differences in the three groups in terms of TyG index,BMI,diabetes,FPG,TC,TG,LDL-C,HDL-C,HbA1c,NT-proBNP,and incidence of endpoint event(P＜0.05,P＜0.01).Univa-riate Cox proportional hazards regression analysis showed that the TyG index,diabetes,and HbA1c were risk factors for endpoint events in elderly patients with UAP(HR=2.523,95％CI:1.593-3.996;HR=2.543,95％CI:1.263-5.118;HR=1.434,95％CI:1.159-1.774).Further multivariate Cox proportional hazards regression analysis showed that,after adjusting for diabetes and HbA1c,the TyG index was an independent risk factor for PCI after discharge in UAP patients(HR=2.023,95％CI:1.209-3.384).Conclusion In elderly UAP patients receiving drug treat-ment,a high TyG index is positively correlated with undergoing PCI after discharge,and the index is an independent risk factor for PCI in them.
