Research progress on the value of splenomegaly in the diagnosis and treatment of biliary atresia
10.3760/cma.j.cn113884-20250305-00075
- VernacularTitle:脾肿大在胆道闭锁诊治中的价值的研究进展
- Author:
Xingyuan KE
1
;
Jiaying LIU
1
;
Yanran ZHANG
1
;
Tengfei LI
1
;
Jianghua ZHAN
1
Author Information
1. 天津市儿童医院（天津大学儿童医院）普外科，天津 300134
- Publication Type:Journal Article
- Keywords:
Biliary atresia;
Liver transplantation;
Splenomegaly;
Kasai procedure;
Portal hypertension
- From:
Chinese Journal of Hepatobiliary Surgery
2025;31(11):867-871
- CountryChina
- Language:Chinese
-
Abstract:
Biliary atresia is often complicated with portal hypertension, which induces a series of hemodynamic changes leading to splenomegaly. Splenomegaly is a common in patients with biliary atresia, which indicates the status of portal hypertension, esophageal varices, and the progression of hepatic fibrosis. Furthermore, it can help monitor the native liver survival status after Kasai procedure and the need for liver transplantation. For patients with biliary atresia presenting splenomegaly and/or hypersplenism, the treatment strategy, involving the pharmacological or surgical options, should be individually selected based on specific clinical condition. This article reviews the value of splenomegaly in the diagnosis and management of biliary atresia, aiming to provide references for clinical practice.
