Research progress on the origin of gut microbiota in liver cancer and its application in diagnosis and treatment
10.3760/cma.j.cn113884-20241112-00332
- VernacularTitle:肝癌瘤内菌群来源及其在诊疗应用中的研究进展
- Author:
Yu CHEN
1
;
Bowen LI
;
Jinhua YANG
;
Hui SU
;
Yang LIU
;
Yunwei WEI
Author Information
1. 宁波大学医学部，宁波 315300
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Intratumoral microbiota;
Tumor microenvironment;
Therapy
- From:
Chinese Journal of Hepatobiliary Surgery
2025;31(5):392-395
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the research on the microbial community within cancer has gradually attracted attention. The microbiota within the tumor affects the immune regulation of liver cancer and may promote the progression of liver cancer through inflammatory responses, metabolic regulation, etc. This article explores the sources and distribution characteristics of microorganisms in liver cancer, their potential mechanism of action in the occurrence and development of liver cancer, and evaluates the application prospects of intratumoral microorganisms in the early diagnosis, treatment response prediction and personalized treatment of liver cancer, especially their potential value in targeted therapy, providing new ideas for microbial intervention in future precision medicine.
