Effects of electroacupuncture combined with hyperbaric oxygen therapy on neural function and cognitive ability in patients with hypertensive cerebral hemorrhage
10.3760/cma.j.cn311847-20191018-00270
- VernacularTitle:电针刺激联合高压氧治疗对高血压脑出血患者神经功能及认知能力的影响
- Author:
Qibing ZHANG
1
;
Feng SHI
;
Fangfang ZHANG
;
Minling ZENG
;
Zhengbiao HUANG
;
Chunbao GUO
;
Xiangyu WANG
;
Aiguo SU
Author Information
1. 443002 湖北省宜昌，三峡大学第三临床医学院·国药葛洲坝中心医院神经内科
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Electroacupuncture;
Hypertensive cerebral hemorrhage;
Neural function;
Cognitive ability
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2020;27(2):188-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of electroacupuncture combined with hyperbaric oxygen (HBO) therapy for the improvement of the neural function and cognitive ability in patients with hypertensive cerebral hemorrhage.Methods:A total of 180 patients with hypertensive cerebral hemorrhage admitted in Department of Neurology of the Sinopharm-Gezhouba Central Hospital of China Three Gorges University from the January of 2016 to the June of 2019 were selected and randomly divided into hyperbaric oxygen group (HBO group) ( n=60), electric acupuncture group (EA group) ( n=60), and EA combined HBO treatment group (EA+ HBO group) ( n=60) by random number table method. The clinical curative effect and the improvements of cerebral edema, neural function, and cognitive ability were compared in the three groups before and after treatment. Results:After 2 and 4 courses of the treatment, the absolute cerebral edema volume and relative cerebral edema volume of the patients were gradually decreased, and the absolute volumes in the EA+ HBO group were significantly decreased compared with those in the HBO group and the EA group with statistically significant differences ( P<0.05). After 4 courses of the treatment, the total effective rate of the EA+ HBO group was 91.67%, which was significantly higher than those of the HBO group (81.67%) and the EA group (76.67%) with statistically significant differences ( P<0.05). The serum neuron-specific enolase (NSE) and S100β levels of the three groups were significantly lower than those before the treatments, and the levels in the EA+ HBO group were lower than those in other two groups. The differences were statistically significant ( P<0.05). After treatment, the mini-mental state examination (MMSE) score and Barthel index score of the patients were significantly increased ( P<0.05), and the improvement of MMSE score in the EA+ HBO group was significantly better than those in the HBO group and the EA group with statistically significant differences ( P<0.05). Conclusion:Electroacupuncture combined with HBO can effectively reduce cerebral edema, repair cerebral nerve damage, and improve patients′ cognitive function through electrical stimulation and abatement of ischemia and hypoxia.
