Study on the short- and mid-term clinical efficacy of covered stents in the treatment of transplanted renal artery stenosis
10.3760/cma.j.cn112149-20241215-00736
- VernacularTitle:覆膜支架治疗移植肾动脉狭窄的近中期临床效果
- Author:
Danghui LU
1
;
Kun LI
;
Dongbin ZHANG
;
Kewei ZHANG
;
Mingzhe CUI
;
Shuiting ZHAI
;
Guoquan WANG
Author Information
1. 郑州大学人民医院 河南省人民医院血管外科，郑州450000
- Publication Type:Journal Article
- Keywords:
Kidney transplant;
Transplant renal artery stenosis;
Radiography, interventional;
Stents
- From:
Chinese Journal of Radiology
2025;59(8):937-941
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the short- and medium-term clinical outcomes of covered stent implantation in the treatment of transplant renal artery stenosis (TRAS).Methods:A retrospective analysis was conducted on the clinical data of 12 consecutive patients with TRAS (transplant renal artery stenosis) who underwent covered stent implantation in Henan Provincial People′s Hospital from January 2021 to December 2024. The changes in indicators such as serum creatinine (Cr), blood urea nitrogen (BUN), mean arterial pressure (MAP), peak systolic velocity (PSV), intrarenal resistance index (RI), and the diameter of the stenotic site were analyzed before the operation, one week after the operation, six months after the operation, and 12 months after the operation. Repeated measures analysis of variance was used to investigate the changes of each observation index over time.Results:The surgery was successfully performed on all 12 patients, with a technical success rate of 100%. Among them, 8 cases used self-expanding covered stents, and 4 cases used balloon-expandable covered stents. One week, six months and twelve months after the surgery, the levels of Cr, BUN, PSV and MAP were all lower than those before the surgery. The RI and the diameter of the stenotic site were significantly increased compared with those before the surgery, the difference was statistically significant ( P<0.05). During the perioperative period and the postoperative follow-up period, no surgery-related complications were found. Conclusion:The implantation of the covered stent can effectively relieve the stenosis of the transplant renal artery, significantly improve renal function, and reduce blood pressure levels in TRAS patients, while maintaining excellent short-to medium-term clinical outcomes.
