Sentinel lymph node perioperative mapping in malignant melanoma
10.3760/cma.j.cn114453-20231113-00214
- VernacularTitle:恶性黑色素瘤前哨淋巴结定位技术
- Author:
Yuxin ZHANG
1
;
Tianyi LIU
1
Author Information
1. 复旦大学附属华东医院整形外科，上海 200040
- Publication Type:Journal Article
- Keywords:
Melanoma;
Sentinel lymph node;
Sentinel lymph node biopsy;
Lymphatic metastasis;
Lymphatic mapping
- From:
Chinese Journal of Plastic Surgery
2025;41(1):74-80
- CountryChina
- Language:Chinese
-
Abstract:
Malignant melanoma, which originates from skin melanocytes, is an extremely aggressive and often lethal malignant skin cancer with early lymphatic metastasis. Sentinel lymph nodes (SLNs) are a group of lymph nodes initially involved in the metastasis. Sentinel lymph node biopsy (SLNB) is a decisive step in the staging process of melanoma and limits the extent of the dissection in negative nodes. Thus, accurately identifying and mapping the micrometastasis in SLNs represents an important prognostic factor. This review highlights the innovation of standard technique entails a preoperative lymphoscintigraphy and an intraoperative mapping using a radiotracer and a blue dye. Moreover, this review summarize the different novel tracers, preoperative and intraoperative imaging modalities assisting SLNB in malignant melanoma as supplements or alternatives to the traditional protocol.
