Optical brain-computer interface: technological advances, clinical translation, and future perspectives
10.12025/j.issn.1008-6358.2026.20260144
- VernacularTitle:光学脑机接口的研究进展、临床转化与未来发展
- Author:
Ang XUAN
1
;
Yuanjie GU
1
;
Yiqun WANG
1
;
Biqin DONG
2
Author Information
1. College of Biomedical Engineering, Fudan University, Shanghai 200433, China.
2. College of Biomedical Engineering, Fudan University, Shanghai 200433, China;Yiwu Research Institute, Fudan University, Jinhua 322000, Zhejiang, China.
- Publication Type:Monographicreport:Technologicalbreakthroughandclinicalapplicationofbrain-computerinterface
- Keywords:
brain-computer interface;
functional near-infrared spectroscopy;
optical neuroimaging;
optogenetics
- From:
Chinese Journal of Clinical Medicine
2026;33(2):193-202
- CountryChina
- Language:Chinese
-
Abstract:
Optical brain-computer interface (OBCI) represents an emerging class of neural interaction technologies that use “light” as an information carrier to enable the acquisition, decoding, and modulation of neural signals. Compared with conventional electrical brain-computer interface (BCI), OBCI demonstrates distinct advantages in spatial resolution, cell-type specificity, and the capacity for simultaneous multiparametric monitoring. Driven by rapid advances in functional near-infrared spectroscopy, optical neuroimaging, and optogenetics, optical approaches have progressively extended across the full “read, decode, write” continuum of neural activity, providing a novel technological framework for the development of high-precision closed-loop brain-computer systems. This review systematically summarizes the principal technological strategies and recent advances in OBCI, and further discusses the key challenges encountered during clinical translation, as well as future development direction.
