A Randomized Controlled Pilot Study on the Effects of Loving-Kindness and Mindfulness Meditation (LKM) on Patients in a Sterile Isolation Room to Improve Their Mood Status

Shinobu YAMADA; Kohki ARIMITSU; Momoko BUYO; Tomoyo MUKAI; Rie NOGUCHI; Akiko MISU; Takashi SONOKI; Makiko HAYASHI

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A Randomized Controlled Pilot Study on the Effects of Loving-Kindness and Mindfulness Meditation (LKM) on Patients in a Sterile Isolation Room to Improve Their Mood Status

VernacularTitle:A Randomized Controlled Pilot Study on the Effects of Loving-Kindness and Mindfulness Meditation (LKM) on Patients in a Sterile Isolation Room to Improve Their Mood Status
Author: Shinobu YAMADA ¹ ; Kohki ARIMITSU ² ; Momoko BUYO ³ ; Tomoyo MUKAI ⁴ ; Rie NOGUCHI ⁴ ; Akiko MISU ⁴ ; Takashi SONOKI ⁵ ; Makiko HAYASHI ⁶
Author Information

1. Wakayama Medical University Graduate School of Health and Nursing Science, Department of Cancer Nursing
2. Kwansei Gakuin University, Department of Psychological Sciences
3. University of Osaka Graduate School of Medicine, Division of Health Sciences, Department of Mental Health Nursing
4. Wakayama Medical University Hospital, Department of Nursing
5. Wakayama Medical University Hospital, Department of Hematology
6. Universal Co., Ltd. Alpha Home-Visit Nursing Station
Keywords: sterile isolation room; loving-kindness; mindfulness; meditation; QOL
From:Japanese Journal of Complementary and Alternative Medicine 2025;22(1):9-17
CountryJapan
Language:English
Abstract: Objective: This study investigates the effectiveness of the Loving-Kindness and Mindfulness Meditation (LKM) therapy in improving mood states of hematologic malignancy patients in a sterile isolation room. A randomized controlled trial was conducted, with the POMS2 Japanese version used to assess mood state improvement. Methods: The final number of participants in this study was nine (intervention group n=4, control group n=5). Patients in a sterile isolation room were provided with a tablet containing a video of the LKM. The intervention group watched the 20-minute video. POMS2 factor scores were measured before the intervention and again one and two weeks after the intervention. The data were analyzed using two-way analysis of variance (ANOVA) to compare the scores across time points. Results: No statistically significant differences were observed between the two groups for each factors; however, a trend of nonlinear change was observed in the Vigor-Apathy (VA) factor(p=0.054). Conclusion: In this pilot study, LKM did not show a significant effect on the mood state of patients, which is suggested to be due to the insufficient number of cases. It seems necessary to increase the number of subjects in future research.