Exploring the Comorbidity Mechanism，Prevention and Treatment Strategies of Rheumatoid Arthritis with Coronary Atherosclerotic Heart Disease Based on Collateral Disease Theory
10.13288/j.11-2166/r.2026.09.006
- VernacularTitle:基于病络理论探讨类风湿关节炎合并冠状动脉粥样硬化性心脏病的共病机制及防治策略
- Author:
Xinning QU
1
;
Hongxiao LIU
1
Author Information
1. Guang'anmen Hospital， China Academy of Chinese Medical Sciences，Beijing，100053
- Publication Type:Journal Article
- Keywords:
rheumatoid arthritis;
coronary atherosclerotic heart disease;
bi （痹） disease;
collateral disease;
different diseases treated in the same way
- From:
Journal of Traditional Chinese Medicine
2026;67(9):951-955
- CountryChina
- Language:Chinese
-
Abstract:
Based on the collateral disease theory， this paper systematically reviews the mechanism laws and the prevention and treatment strategies for the comorbidity of rheumatoid arthritis （RA） and coronary heart disease （CHD）. It is believed that the collateral vessels serve as the core pathways connecting the limbs and joints with the zang-fu （脏腑） organs. The comorbidity of RA and CHD follows a progressive transmission pattern from wang bi （尪痹）， vessel bi （脉痹） to heart bi （心痹）. In this sequence， wang bi refers to damp-heat obstructing the qi collaterals of the limbs and joints. Vessel bi is characterized by the binding of phlegm and stasis， along with hyperactive changes in the collateral pathways， and pathogenic factors penetrating the blood vessels. Heart bi occurs when latent toxins damage the collaterals and lead to failure of heart yang. In terms of prevention and treatment strategies， the principle of "treating disease before it arises" should be adopted as guidance， taking overall therapeutic goal as preventing pathogenic factors from penetrating inward along the collaterals， that is from the body surface and limbs into the zang-fu organs. At the wang bi stage， treatment focuses on clearing heat and draining dampness， diffusing and unblocking qi collaterals， while at the vessel bi stage， it is recommended to clear up phlegm， dissolve stasis， and unblock blood collaterals. At the heart bi stage， treatment should focus on activating blood and unblocking the collaterals， restoring yang and diffusing bi.
