A case of transmodiolar intralabyrinthine schwannoma (ILS) in a 51-year-old woman.

Matthew Alain J HERNANDEZ; Nathaniel W YANG

Return

A case of transmodiolar intralabyrinthine schwannoma (ILS) in a 51-year-old woman.

Author: Matthew Alain J. HERNANDEZ ¹ ; Nathaniel W. YANG ²
Author Information

1. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Philippine General Hospital, Manila, Metro Manila, NCR, Philippines
2. Department of Otolaryngology-Head and Neck Surgery, Far Eastern University - Nicanor Reyes Medical Foundation Institute of Medicine, Quezon City, Metro Manila, NCR, Philippines
Publication Type:Case Report
Keywords: Intralabyrinthine; Transmodiolar; Intracochlear; Vestibular; Labyrinthine
MeSH: Human; Female; Middle Aged: 45-64 Yrs Old; Neurilemmoma; Schwannoma
From: Philippine Journal of Otolaryngology Head and Neck Surgery 2025;40(2):47-50
CountryPhilippines
Abstract: OBJECTIVES
To highlight the clinical presentation, diagnostic dilemma and proposed management of a case of a transmodiolar intralabyrinthine schwannoma.
METHODS
Design:Case Report
Setting:Tertiary National University Hospital
Patient:One
RESULTS
A 51-year-old woman consulted for a 12-year history of unilateral sensorineural hearing loss and progressively worsening vertigo. Workups revealed a hyperintense lesion approximating the entire right cochlea on Gadolinium-enhanced magnetic resonance imaging and profound hearing loss on the right on pure-tone audiometry, with no recordable response even at maximum intensity levels across all frequencies. Infectious and metastatic workups returned negative results, clinching the radiographic diagnosis of an intralabyrinthine schwannoma.
CONCLUSION
Intralabyrinthine schwannomas (ILS) are rare, benign neoplasms of the 8th cranial nerve, manifesting as progressive unilateral sensorineural hearing loss and worsening vertigo. These neoplasms are mainly detected by MRI; underdiagnosis and lack of standard treatment and diagnostic protocols result in their inaccurate diagnosis and delays in management.